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A Modified EpiSC Culture Condition Containing a GSK3 Inhibitor Can Support Germline-Competent Pluripotency in Mice

Embryonic stem cells (ESCs) can contribute to the tissues of chimeric animals, including the germline. By contrast, epiblast stem cells (EpiSCs) barely contribute to chimeras. These two types of cells are established and maintained under different culture conditions. Here, we show that a modified Ep...

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Bibliografski detalji
Glavni autori: Tsukiyama, Tomoyuki, Ohinata, Yasuhide
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988182/
https://ncbi.nlm.nih.gov/pubmed/24736627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095329
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