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A Modified EpiSC Culture Condition Containing a GSK3 Inhibitor Can Support Germline-Competent Pluripotency in Mice

Embryonic stem cells (ESCs) can contribute to the tissues of chimeric animals, including the germline. By contrast, epiblast stem cells (EpiSCs) barely contribute to chimeras. These two types of cells are established and maintained under different culture conditions. Here, we show that a modified Ep...

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Bibliografiset tiedot
Päätekijät: Tsukiyama, Tomoyuki, Ohinata, Yasuhide
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988182/
https://ncbi.nlm.nih.gov/pubmed/24736627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095329
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