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A Modified EpiSC Culture Condition Containing a GSK3 Inhibitor Can Support Germline-Competent Pluripotency in Mice

Embryonic stem cells (ESCs) can contribute to the tissues of chimeric animals, including the germline. By contrast, epiblast stem cells (EpiSCs) barely contribute to chimeras. These two types of cells are established and maintained under different culture conditions. Here, we show that a modified Ep...

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Hlavní autoři: Tsukiyama, Tomoyuki, Ohinata, Yasuhide
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988182/
https://ncbi.nlm.nih.gov/pubmed/24736627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095329
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