Knockdown of Zebrafish Lumican Gene (zlum) Causes Scleral Thinning and Increased Size of Scleral Coats

The lumican gene (lum), which encodes one of the major keratan sulfate proteoglycans (KSPGs) in the vertebrate cornea and sclera, has been linked to axial myopia in humans. In this study, we chose zebrafish (Danio rerio) as an animal model to elucidate the role of lumican in the development of axial...

Full description

Saved in:
Bibliographic Details
Main Authors: Yeh, Lung-Kun, Liu, Chia-Yang, Kao, Winston W.-Y., Huang, Chang-Jen, Hu, Fung-Rong, Chien, Chung-Liang, Wang, I-Jong
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934679/
https://ncbi.nlm.nih.gov/pubmed/20551313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.043679
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items