Structural Analysis of Saccharomyces cerevisiae α-Galactosidase and Its Complexes with Natural Substrates Reveals New Insights into Substrate Specificity of GH27 Glycosidases

α-Galactosidases catalyze the hydrolysis of terminal α-1,6-galactosyl units from galacto-oligosaccharides and polymeric galactomannans. The crystal structures of tetrameric Saccharomyces cerevisiae α-galactosidase and its complexes with the substrates melibiose and raffinose have been determined to...

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Bibliografske podrobnosti
Main Authors: Fernández-Leiro, Rafael, Pereira-Rodríguez, Ángel, Cerdán, M. Esperanza, Becerra, Manuel, Sanz-Aparicio, Juliana
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Protein Structure and Folding
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934667/
https://ncbi.nlm.nih.gov/pubmed/20592022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.144584
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