p53 associates with and targets ΔNp63 into a protein degradation pathway

A human p53 homologue, p63 (p40/p51/p73L/CUSP) that maps to the chromosomal region 3q27–29 was found to produce a variety of transcripts that encode DNA-binding proteins with and without a trans-activation domain (TA- or ΔN-, respectively). The p63 gene locus was found to be amplified in squamous ce...

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Главные авторы: Ratovitski, Edward A., Patturajan, Meera, Hibi, Kenji, Trink, Barry, Yamaguchi, Kengo, Sidransky, David
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2001
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC29340/
https://ncbi.nlm.nih.gov/pubmed/11172034
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