THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves

THAP-family C(2)CH zinc-coordinating DNA-binding proteins function in diverse eukaryotic cellular processes, such as transposition, transcriptional repression, stem-cell pluripotency, angiogenesis and neurological function. To determine the molecular basis for sequence-specific DNA recognition by TH...

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Bibliographic Details
Main Authors: Sabogal, Alex, Lyubimov, Artem Y., Corn, Jacob E., Berger, James M., Rio, Donald C.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933787/
https://ncbi.nlm.nih.gov/pubmed/20010837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1742
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