Lentiviral Overexpression of GRK6 Alleviates L-Dopa–Induced Dyskinesia in Experimental Parkinson’s Disease

Parkinson’s disease is caused primarily by degeneration of brain dopaminergic neurons in the substantia nigra and the consequent deficit of dopamine in the striatum. Dopamine replacement therapy with the dopamine precursor L-dopa is the mainstay of current treatment. After several years, however, th...

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Auteurs principaux: Ahmed, Mohamed R., Berthet, Amandine, Bychkov, Evgeny, Porras, Gregory, Li, Qin, Bioulac, Bernard H., Carl, Yonatan T., Bloch, Bertrand, Kook, Seunghyi, Aubert, Incarnation, Dovero, Sandra, Doudnikoff, Evelyne, Gurevich, Vsevolod V., Gurevich, Eugenia V., Bezard, Erwan
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933751/
https://ncbi.nlm.nih.gov/pubmed/20410529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000664
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