Somatic Expression of PyMT or Activated ErbB2 Induces Estrogen-Independent Mammary Tumorigenesis

Estrogen signaling is required for the proliferation of normal breast epithelial cells. However, prophylactic inhibition of estrogen signaling fails to prevent 56% of human breast cancer cases. The underlying mechanism is not well understood. Aberrant activation of growth factor signaling is known t...

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Bibliografische gegevens
Hoofdauteurs: Toneff, Michael J, Du, Zhijun, Dong, Jie, Huang, Jian, Sinai, Parisa, Forman, James, Hilsenbeck, Susan, Schiff, Rachel, Huang, Shixia, Li, Yi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Neoplasia Press Inc. 2010
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933692/
https://ncbi.nlm.nih.gov/pubmed/20824048
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