Somatic Expression of PyMT or Activated ErbB2 Induces Estrogen-Independent Mammary Tumorigenesis

Estrogen signaling is required for the proliferation of normal breast epithelial cells. However, prophylactic inhibition of estrogen signaling fails to prevent 56% of human breast cancer cases. The underlying mechanism is not well understood. Aberrant activation of growth factor signaling is known t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Toneff, Michael J, Du, Zhijun, Dong, Jie, Huang, Jian, Sinai, Parisa, Forman, James, Hilsenbeck, Susan, Schiff, Rachel, Huang, Shixia, Li, Yi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Neoplasia Press Inc. 2010
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933692/
https://ncbi.nlm.nih.gov/pubmed/20824048
Tagiau: Ychwanegu Tag
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