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Rb regulates fate choice and lineage commitment in vivo
Mutation of the RB-1 tumour suppressor occurs in one third of all human tumours and is particularly associated with retinoblastoma and osteosarcoma1. Numerous functions have been ascribed to the product of the human RB-1 gene, pRB. The best known is pRB’s ability to promote cell cycle exit through i...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933655/ https://ncbi.nlm.nih.gov/pubmed/20686481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09264 |
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