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Critical role for the catalytic activity of phospholipase C-γ1 in epidermal growth factor-induced cell migration

Phospholipase C-γ1 (PLC-γ1), a tyrosine kinase substrate, has been implicated in the pathway for the epidermal growth factor receptor (EGFR)-induced cell migration. However, the underlying mechanism by which PLC-γ1 mediates EGFR-induced cell migration remains elusive. In the present study, we sought...

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Detalhes bibliográficos
Main Authors: Xie, Zhongjian, Peng, Jian, Pennypacker, Sally D., Chen, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933433/
https://ncbi.nlm.nih.gov/pubmed/20674545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.07.098
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