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Phospholipase C-γ1 is Required for the Epidermal Growth Factor Receptor-induced Squamous Cell Carcinoma Cell Mitogenesis

The epidermal growth factor receptor (EGFR) is a key driver in the process of squamous cell carcinoma (SCC) cell mitogenesis. Phospholipase C-γ1 (PLC-γ1) is a downstream target of EGFR signaling, but the role and necessity of PLC-γ1 in EGFR-induced cell mitogenesis remain unclear. In the present stu...

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Detalhes bibliográficos
Main Authors: Xie, Zhongjian, Chen, Ying, Liao, Er-Yuan, Jiang, Yi, Liu, Fu-You, Pennypacker, Sally D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901589/
https://ncbi.nlm.nih.gov/pubmed/20510673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.05.103
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