Reduced expression of E-cadherin and p120-catenin and elevated expression of PLC-γ1 and PIKE are associated with aggressiveness of oral squamous cell carcinoma

Oral squamous cell carcinoma (OSCC) is one of the most lethal malignant tumors. The cadherin/catenin cell-cell adhesion complex plays a major role in cancer development and progression. p120-catenin (p120) is a cytoplasmic molecule closely associated with E-cadherin which activates phospholipase C-γ...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Jiang, Yi, Liao, Liyan, Shrestha, Chandrama, Ji, Shangli, Chen, Ying, Peng, Jian, Wang, Larry, Liao, Eryuan, Xie, Zhongjian
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583878/
https://ncbi.nlm.nih.gov/pubmed/26464646
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