Ultraviolet radiation inhibits 15-hydroxyprostaglandin dehydrogenase levels in human skin: evidence of transcriptional suppression

Elevated levels of prostaglandins (PGs) have been detected in skin following ultraviolet radiation (UVR). Prostaglandins play an important role in mediating both the acute and chronic consequences of UVR exposure. UVR-mediated induction of cyclooxygenase-2 (COX-2) contributes to increased PG synthes...

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Autori principali: Judson, Benjamin L., Miyaki, Akira, Kekatpure, Vikram D., Du, Baoheng, Gilleaudeau, Patricia, Sullivan-Whalen, Mary, Mohebati, Arash, Nair, Sudhir, Boyle, Jay O., Granstein, Richard D., Subbaramaiah, Kotha, Krueger, James G., Dannenberg, Andrew J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933319/
https://ncbi.nlm.nih.gov/pubmed/20643784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0089
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