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Manduca sexta serpin-5 regulates prophenoloxidase activation and the Toll signaling pathway by inhibiting hemolymph proteinase HP6
Insect immune responses include prophenoloxidase (proPO) activation and Toll pathway initiation, which are mediated by serine proteinase cascades and regulated by serpins. Manduca sexta hemolymph proteinase 6 (HP6) is a component of both pathways. It cleaves and activates proPO activating proteinase...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933306/ https://ncbi.nlm.nih.gov/pubmed/20624461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ibmb.2010.07.001 |
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