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Manduca sexta serpin-5 regulates prophenoloxidase activation and the Toll signaling pathway by inhibiting hemolymph proteinase HP6

Insect immune responses include prophenoloxidase (proPO) activation and Toll pathway initiation, which are mediated by serine proteinase cascades and regulated by serpins. Manduca sexta hemolymph proteinase 6 (HP6) is a component of both pathways. It cleaves and activates proPO activating proteinase...

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Detalhes bibliográficos
Main Authors: An, Chunju, Kanost, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933306/
https://ncbi.nlm.nih.gov/pubmed/20624461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ibmb.2010.07.001
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