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Activation of macrophages by P2X(7)-induced microvesicles from myeloid cells is mediated by phospholipids and is partially dependent on TLR4
ATP-mediated activation of the purinergic receptor P2X(7) elicits morphological changes and pro-inflammatory responses in macrophages. These changes include rapid shedding of microvesicles (MV), and the non-conventional secretion of cytokines, such as IL-1β and IL-18 following priming. Here we demon...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933301/ https://ncbi.nlm.nih.gov/pubmed/20709956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001231 |
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