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Direct and Indirect Roles of the LTβR Pathway in Central Tolerance Induction

Medullary thymic epithelial cells (mTECs) play a critical role in thymic negative selection of autoreactive thymocytes, especially for thymocytes specific for peripheral tissue-restricted self-antigens (TRA). Deficiency in LTβR is associated with peripheral tissue inflammation but whether it is caus...

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Bibliografiske detaljer
Main Authors: Zhu, Mingzhao, Brown, Nicholas K., Fu, Yang-Xin
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933296/
https://ncbi.nlm.nih.gov/pubmed/20675191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2010.06.005
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