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The matrix metalloproteinase stromelysin-1 acts as a natural mammary tumor promoter

Extracellular matrix-degrading matrix metalloproteinases (MMPs) are invariably upregulated in epithelial cancers and are key agonists in angiogenesis, invasion and metastasis. Yet most MMPs are secreted not by the cancer cells themselves, but by stromal cells within and around the tumor mass. Becaus...

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Sonraí Bibleagrafaíochta
Main Authors: Sternlicht, Mark D, Bissell, Mina J, Werb, Zena
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2000
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933206/
https://ncbi.nlm.nih.gov/pubmed/10713697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1203347
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