The Stromal Proteinase MMP3/Stromelysin-1 Promotes Mammary Carcinogenesis

Matrix metalloproteinases (MMPs) are invariably upregulated in the stromal compartment of epithelial cancers and appear to promote invasion and metastasis. Here we report that phenotypically normal mammary epithelial cells with tetracycline-regulated expression of MMP3/stromelysin-1 (Str1) form epit...

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Auteurs principaux: Sternlicht, Mark D., Lochter, Andre, Sympson, Carolyn J., Huey, Bing, Rougier, Jean-Philippe, Gray, Joe W., Pinkel, Dan, Bissell, Mina J., Werb, Zena
Format: Artigo
Langue:Inglês
Publié: 1999
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853255/
https://ncbi.nlm.nih.gov/pubmed/10428026
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