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The matrix metalloproteinase stromelysin-1 acts as a natural mammary tumor promoter
Extracellular matrix-degrading matrix metalloproteinases (MMPs) are invariably upregulated in epithelial cancers and are key agonists in angiogenesis, invasion and metastasis. Yet most MMPs are secreted not by the cancer cells themselves, but by stromal cells within and around the tumor mass. Becaus...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2000
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933206/ https://ncbi.nlm.nih.gov/pubmed/10713697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1203347 |
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