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The matrix metalloproteinase stromelysin-1 acts as a natural mammary tumor promoter

Extracellular matrix-degrading matrix metalloproteinases (MMPs) are invariably upregulated in epithelial cancers and are key agonists in angiogenesis, invasion and metastasis. Yet most MMPs are secreted not by the cancer cells themselves, but by stromal cells within and around the tumor mass. Becaus...

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Detalles Bibliográficos
Main Authors: Sternlicht, Mark D, Bissell, Mina J, Werb, Zena
Formato: Artigo
Idioma:Inglês
Publicado: 2000
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933206/
https://ncbi.nlm.nih.gov/pubmed/10713697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1203347
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