Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65)

T cell recognition of autoantigens is critical to progressive immune-mediated destruction of islet cells, which leads to autoimmune diabetes. We identified a naturally presented autoantigen from the human islet antigen glutamic acid decarboxylase, 65-kDa isoform (GAD65), by using a combination of ch...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Nepom, Gerald T., Lippolis, John D., White, Forest M., Masewicz, Susan, Marto, Jarrod A., Herman, Andrew, Luckey, C. John, Falk, Ben, Shabanowitz, Jeffrey, Hunt, Donald F., Engelhard, Victor H., Nepom, Barbara S.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2001
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC29331/
https://ncbi.nlm.nih.gov/pubmed/11172025
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires