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Functional diversity of ES cell derived motor neuron subtypes revealed through intraspinal transplantation

Cultured ES cells can form different classes of neurons, but whether these neurons can acquire specialized subtype features typical of neurons in vivo remains unclear. We show here that mouse ES cells can be directed to form highly specific motor neuron subtypes in the absence of added factors, thro...

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Autori principali: Peljto, Mirza, Dasen, Jeremy S., Mazzoni, Esteban O., Jessell, Thomas M., Wichterle, Hynek
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933095/
https://ncbi.nlm.nih.gov/pubmed/20804971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.07.013
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