Functional diversity of ES cell derived motor neuron subtypes revealed through intraspinal transplantation

Cultured ES cells can form different classes of neurons, but whether these neurons can acquire specialized subtype features typical of neurons in vivo remains unclear. We show here that mouse ES cells can be directed to form highly specific motor neuron subtypes in the absence of added factors, thro...

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Bibliographic Details
Main Authors: Peljto, Mirza, Dasen, Jeremy S., Mazzoni, Esteban O., Jessell, Thomas M., Wichterle, Hynek
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933095/
https://ncbi.nlm.nih.gov/pubmed/20804971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.07.013
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