Integrin-Linked Kinase Is a Functional Mn(2+)-Dependent Protein Kinase that Regulates Glycogen Synthase Kinase-3β (GSK-3β) Phosphorylation

BACKGROUND: Integrin-linked kinase (ILK) is a highly evolutionarily conserved, multi-domain signaling protein that localizes to focal adhesions, myofilaments and centrosomes where it forms distinct multi-protein complexes to regulate cell adhesion, cell contraction, actin cytoskeletal organization a...

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Bibliografiska uppgifter
Huvudupphovsmän: Maydan, Mykola, McDonald, Paul C., Sanghera, Jasbinder, Yan, Jun, Rallis, Charalampos, Pinchin, Sheena, Hannigan, Gregory E., Foster, Leonard J., Ish-Horowicz, David, Walsh, Michael P., Dedhar, Shoukat
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932980/
https://ncbi.nlm.nih.gov/pubmed/20827300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012356
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