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In Vivo Regulation of Glycogen Synthase Kinase-3β (GSK3β) by Serotonergic Activity in Mouse Brain

The goal of this study was to determine if serotonergic activity, which is impaired in depression, regulates the phosphorylation of glycogen synthase kinase-3β (GSK3β) in mouse brain in vivo. GSK3β is inhibited by phosphorylation on serine-9 and is a target of the mood stabilizer lithium. Following...

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Detalhes bibliográficos
Main Authors: Li, Xiaohua, Zhu, Wawa, Roh, Myoung-Sun, Friedman, Ari B, Rosborough, Kelley, Jope, Richard S
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986663/
https://ncbi.nlm.nih.gov/pubmed/15039769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.npp.1300439
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