Integrin-linked kinase: both Jekyll and Hyde in rhabdomyosarcoma

per McDonald, Paul C., Dedhar, Shoukat, Keller, Charles
Publicat 2009

Coordinated Regulation of Metabolic Transporters and Migration/Invasion by Carbonic Anhydrase IX

per McDonald, Paul C., Swayampakula, Mridula, Dedhar, Shoukat
Publicat a Metabolites (2018)

Overcoming Hypoxia-Mediated Tumor Progression: Combinatorial Approaches Targeting pH Regulation, Angiogenesis and Immune Dysfunction

per McDonald, Paul C., Chafe, Shawn C., Dedhar, Shoukat
Publicat a Front Cell Dev Biol (2016)

Recent Developments in Targeting Carbonic Anhydrase IX for Cancer Therapeutics

per McDonald, Paul C., Winum, Jean-Yves, Supuran, Claudiu T., Dedhar, Shoukat
Publicat 2012

Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase

per Serrano, Isabel, McDonald, Paul C., Lock, Frances, Muller, William J., Dedhar, Shoukat
Publicat 2013

Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization

per Fielding, Andrew B., Dobreva, Iveta, McDonald, Paul C., Foster, Leonard J., Dedhar, Shoukat
Publicat 2008

Harnessing Induced Essentiality: Targeting Carbonic Anhydrase IX and Angiogenesis Reduces Lung Metastasis of Triple Negative Breast Cancer Xenografts

per Hedlund, Eva-Maria E., McDonald, Paul C., Nemirovsky, Oksana, Awrey, Shannon, Jensen, Lasse D.E., Dedhar, Shoukat
Publicat a Cancers (Basel) (2019)

A novel inhibitory effect of oxazol-5-one compounds on ROCKII signaling in human coronary artery vascular smooth muscle cells

per Al-Ghabkari, Abdulhameed, Deng, Jing-Ti, McDonald, Paul C., Dedhar, Shoukat, Alshehri, Mana, Walsh, Michael P., MacDonald, Justin A.
Publicat a Sci Rep (2016)

β1 integrin, ILK and mTOR regulate collagen synthesis in mechanically loaded tendon cells

per Mousavizadeh, Rouhollah, Hojabrpour, Payman, Eltit, Felipe, McDonald, Paul C., Dedhar, Shoukat, McCormack, Robert G., Duronio, Vincent, Jafarnejad, Seyed Mehdi, Scott, Alex
Publicat a Sci Rep (2020)

A Phase 1 Study of SLC-0111, a Novel Inhibitor of Carbonic Anhydrase IX, in Patients With Advanced Solid Tumors

per McDonald, Paul C., Chia, Stephen, Bedard, Philippe L., Chu, Quincy, Lyle, Michael, Tang, Liren, Singh, Madhu, Zhang, Zaihui, Supuran, Claudiu T., Renouf, Daniel J., Dedhar, Shoukat
Publicat a Am J Clin Oncol (2020)

Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer

per Brown, Wells S., McDonald, Paul C., Nemirovsky, Oksana, Awrey, Shannon, Chafe, Shawn C., Schaeffer, David F., Li, Jinyang, Renouf, Daniel J., Stanger, Ben Z., Dedhar, Shoukat
Publicat a Cell Rep Med (2020)

Integrin-Linked Kinase Is a Functional Mn(2+)-Dependent Protein Kinase that Regulates Glycogen Synthase Kinase-3β (GSK-3β) Phosphorylation

per Maydan, Mykola, McDonald, Paul C., Sanghera, Jasbinder, Yan, Jun, Rallis, Charalampos, Pinchin, Sheena, Hannigan, Gregory E., Foster, Leonard J., Ish-Horowicz, David, Walsh, Michael P., Dedhar, Shoukat
Publicat 2010

Tetraspanin 8 is a novel regulator of ILK-driven β1 integrin adhesion and signaling in invasive melanoma cells

per Kharbili, Manale El, Robert, Clément, Witkowski, Tiffany, Danty-Berger, Emmanuelle, Barbollat-Boutrand, Laetitia, Masse, Ingrid, Gadot, Nicolas, de la Fouchardière, Arnaud, McDonald, Paul C, Dedhar, Shoukat, Le Naour, François, Degoul, Françoise, Berthier-Vergnes, Odile
Publicat a Oncotarget (2017)

LIMD2 Is a Small LIM-Only Protein Overexpressed in Metastatic Lesions That Regulates Cell Motility and Tumor Progression by Directly Binding to and Activating the Integrin-Linked K...

per Peng, Hongzhuang, Talebzadeh-Farrooji, Mehdi, Osborne, Michael J., Prokop, Jeremy W., McDonald, Paul C., Karar, Jayashree, Hou, Zhaoyuan, He, Mei, Kebebew, Electron, Orntoft, Torben, Herlyn, Meenhard, Caton, Andrew J., Fredericks, William, Malkowicz, Bruce, Paterno, Christopher S., Carolin, Alexandra S., Speicher, David W., Skordalakes, Emmanuel, Huang, Qihong, Dedhar, Shoukat, Borden, Katherine L.B., Rauscher, Frank J.
Publicat 2014

Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo

per Boyd, Nathaniel H., Walker, Kiera, Fried, Joshua, Hackney, James R., McDonald, Paul C., Benavides, Gloria A., Spina, Raffaella, Audia, Alessandra, Scott, Sarah E., Landis, Catherine J., Tran, Anh Nhat, Bevensee, Mark O., Griguer, Corinne, Nozell, Susan, Gillespie, G. Yancey, Nabors, Burt, Bhat, Krishna P., Bar, Eli E., Darley-Usmar, Victor, Xu, Bo, Gordon, Emily, Cooper, Sara J., Dedhar, Shoukat, Hjelmeland, Anita B.
Publicat a JCI Insight (2017)