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A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability

In response to DNA damage, cells activate a complex signal transduction network called the DNA damage response (DDR). To enhance our current understanding of the DDR network, we performed a genome-wide RNAi screen to identify genes required for resistance to ionizing radiation (IR). Along with a num...

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Bibliografske podrobnosti
Main Authors: Hurov, Kristen E., Cotta-Ramusino, Cecilia, Elledge, Stephen J.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932975/
https://ncbi.nlm.nih.gov/pubmed/20810650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1934210
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