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Bovine Serum Albumin-Catalyzed Deprotonation of [1-(13)C]-Glycolaldehyde: Protein Reactivity Toward Deprotonation of α–Hydroxy α–Carbonyl Carbon

Bovine serum albumin (BSA) in D(2)O at 25 °C and pD 7.0 was found to catalyze the deuterium exchange reactions of [1-(13)C]-glycolaldehyde ([1-(13)C]-GA) to form [1-(13)C, 2-(2)H]-GA and [1-(13)C, 2,2-di-(2)H]-GA. The formation of [1-(13)C, 2-(2)H]-GA and [1-(13)C, 2,2-di-(2)H]-GA in a total yield o...

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Detalhes bibliográficos
Main Authors: Go, Maybelle K., Malabanan, M. Merced, Amyes, Tina L., Richard, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932853/
https://ncbi.nlm.nih.gov/pubmed/20687575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101118g
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