Llwytho...

Chromatin remodeling is required for gene reactivation after Decitabine-mediated DNA hypomethylation

The DNA hypomethylating drug Decitabine (DAC) reactivates silenced gene expression in cancer and is approved for the treatment of the myelodysplastic syndrome. Gene reactivation after DAC is variable and incompletely understood. Here, we established a cell line system (YB5) derived from the SW48 col...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Si, Jiali, Boumber, Yanis A., Shu, Jingmin, Qin, Taichun, Ahmed, Saira, He, Rong, Jelinek, Jaroslav, Issa, Jean-Pierre J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932851/
https://ncbi.nlm.nih.gov/pubmed/20713525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4474
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