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Mechanisms of Resistance to Decitabine in the Myelodysplastic Syndrome
PURPOSE: The DNA methylation inhibitor 5-aza-2′-deoxycytidine (DAC) is approved for the treatment of myelodysplastic syndromes (MDS), but resistance to DAC develops during treatment and mechanisms of resistance remain unknown. Therefore, we investigated mechanisms of primary and secondary resistance...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3157379/ https://ncbi.nlm.nih.gov/pubmed/21858090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023372 |
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