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Biliary apotopes and anti-mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis
Our understanding of primary biliary cirrhosis (PBC) has been significantly enhanced by the rigorous dissection of the multilineage T and B cell response against the immunodominant mitochondrial autoantigen, the E2 component of the pyruvate dehydrogenase complex (PDC-E2). PDC-E2 is a ubiquitous prot...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2932809/ https://ncbi.nlm.nih.gov/pubmed/20568301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23783 |
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