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Structure-Activity Relationship Analysis of Peptides Targeting the EphA2 Receptor

The EphA2 receptor tyrosine kinase has emerged as a promising new therapeutic target in cancer due to its high expression in tumors. EphA2-specific antibodies have been used to deliver drugs and toxins to tumor cells, leading to inhibition of tumor growth and metastatic dissemination. We previously...

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Hlavní autoři: Mitra, Sayantan, Duggineni, Srinivas, Koolpe, Mitchell, Zhu, Xuejun, Huang, Ziwei, Pasquale, Elena B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932750/
https://ncbi.nlm.nih.gov/pubmed/20677833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1006223
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