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Direct, help-independent priming of CD8+ T cells by AAV-transduced hepatocytes

Both HBV and HCV frequently establish chronic infection, raising the question whether T cells are poorly primed in the liver. To determine the role of different cell types in the activation of CD8+ T cells against hepatocellular antigens, we used an Adeno-Associated Virus to deliver ovalbumin to hep...

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Autors principals: Wuensch, Sherry A., Spahn, Jessica, Crispe, Ian N.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932746/
https://ncbi.nlm.nih.gov/pubmed/20607836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23745
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