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Myeloid Differentiation Factor 88 (MyD88)-Deficiency Increases Risk of Diabetes in Mice

BACKGROUND: Multiple lines of evidence suggest innate immune response pathways to be involved in the development of obesity-associated diabetes although the molecular mechanism underling the disease is unknown. Recent observations suggest that saturated fatty acids can act as a ligand for toll-like...

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Hlavní autoři: Hosoi, Toru, Yokoyama, Shota, Matsuo, Suguru, Akira, Shizuo, Ozawa, Koichiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932727/
https://ncbi.nlm.nih.gov/pubmed/20824098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012537
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