Učitavanje...
A family of diiron monooxygenases catalyzing amino acid beta-hydroxylation in antibiotic biosynthesis
The biosynthesis of chloramphenicol requires a β-hydroxylation tailoring reaction of the precursor L-p-aminophenylalanine (L-PAPA). Here, it is shown that this reaction is catalyzed by the enzyme CmlA from an operon containing the genes for biosynthesis of L-PAPA and the nonribosomal peptide synthet...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2932612/ https://ncbi.nlm.nih.gov/pubmed/20713732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1007953107 |
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