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Proton and cation transport activity of the M2 proton channel from influenza A virus

The M2 protein is a small, single-span transmembrane (TM) protein from the influenza A virus. This virus enters cells via endosomes; as the endosomes mature and become more acidic M2 facilitates proton transport into the viral interior, thereby disrupting matrix protein/RNA interactions required for...

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Bibliographische Detailangaben
Hauptverfasser: Leiding, Thom, Wang, Jun, Martinsson, Jonas, DeGrado, William F., Årsköld, Sindra Peterson
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932607/
https://ncbi.nlm.nih.gov/pubmed/20713739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009997107
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