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Six and Eya promote apoptosis through direct transcriptional activation of the proapoptotic BH3-only gene egl-1 in Caenorhabditis elegans

The decision of a cell to undergo programmed cell death is tightly regulated during animal development and tissue homeostasis. Here, we show that the Caenorhabditis elegans Six family homeodomain protein C. elegans homeobox (CEH-34) and the Eyes absent ortholog EYA-1 promote the programmed cell deat...

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Detalhes bibliográficos
Main Authors: Hirose, Takashi, Galvin, Brendan D., Horvitz, H. Robert
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932601/
https://ncbi.nlm.nih.gov/pubmed/20713707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010023107
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