Phosphorylation of the Proapoptotic BH3-Only Protein Bid Primes Mitochondria for Apoptosis during Mitotic Arrest

Mitosis is a moment of exquisite vulnerability for a metazoan cell. Failure to complete mitosis accurately can lead to aneuploidy and cancer initiation. Therefore, if the exit from mitosis is delayed, normal cells are usually removed by apoptosis. However, how failure to complete mitosis activates a...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Pengbo, Lindsay, Jennefer, Owens, Thomas W., Mularczyk, Ewa J., Warwood, Stacey, Foster, Fiona, Streuli, Charles H., Brennan, Keith, Gilmore, Andrew P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cell Press 2014
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022835/
https://ncbi.nlm.nih.gov/pubmed/24767991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.03.050
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