Long-lasting humoral and cellular immune responses and mucosal dissemination after intramuscular DNA immunization

Naïve Indian rhesus macaques were immunized with a mixture of optimized plasmid DNAs expressing several SIV antigens using in vivo electroporation via the intramuscular route. The animals were monitored for the development of SIV-specific systemic (blood) and mucosal (bronchoalveolar lavage) cellula...

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Autors principals: Patel, Vainav, Valentin, Antonio, Kulkarni, Viraj, Rosati, Margherita, Bergamaschi, Cristina, Jalah, Rashmi, Alicea, Candido, Minang, Jacob T., Trivett, Matthew T., Ohlen, Claes, Zhao, Jun, Robert-Guroff, Marjorie, Khan, Amir S., Draghia-Akli, Ruxandra, Felber, Barbara K., Pavlakis, George N.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932451/
https://ncbi.nlm.nih.gov/pubmed/20451642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.04.064
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