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Chemical versus Mechanical Perturbations on the Protonation State of Arginine in Complex Lipid Membranes: Insights from Microscopic pK(a) Calculations

Charged amino acids such as Arginine play important roles in many membrane-mediated biological processes such as voltage gating of ion channels and membrane translocation of cell penetration peptides. It is well established that local membrane deformation and formation of water defects are crucial t...

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Библиографические подробности
Главные авторы: Yoo, Jejoong, Cui, Qiang
Формат: Artigo
Язык:Inglês
Опубликовано: The Biophysical Society 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931746/
https://ncbi.nlm.nih.gov/pubmed/20816065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.048
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