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Chemical versus Mechanical Perturbations on the Protonation State of Arginine in Complex Lipid Membranes: Insights from Microscopic pK(a) Calculations
Charged amino acids such as Arginine play important roles in many membrane-mediated biological processes such as voltage gating of ion channels and membrane translocation of cell penetration peptides. It is well established that local membrane deformation and formation of water defects are crucial t...
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Biophysical Society
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2931746/ https://ncbi.nlm.nih.gov/pubmed/20816065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.048 |
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