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Characterizing Single-Channel Behavior of GluA3 Receptors

AMPA receptors play a major role in excitatory neurotransmission in the CNS and are involved in numerous neurological disorders. Agonists bind to each of four bilobed LBDs of this tetrameric receptor, and upon binding, the lobes close to envelope the agonist, leading to channel activation. However,...

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Detalhes bibliográficos
Main Authors: Poon, Kinning, Nowak, Linda M., Oswald, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931745/
https://ncbi.nlm.nih.gov/pubmed/20816055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.058
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