Detecting Protein Aggregates on Untreated Human Tissue Samples by Atomic Force Microscopy Recognition Imaging

We apply topography and recognition (TREC) imaging to the analysis of whole, untreated human tissue for what we believe to be the first time. Pseudoexfoliation syndrome (PEX), a well-known cause of irreversible blindness worldwide, is characterized by abnormal protein aggregation on the anterior len...

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Bibliografiske detaljer
Main Authors: Creasey, Rhiannon, Sharma, Shiwani, Craig, Jamie E., Gibson, Christopher T., Ebner, Andreas, Hinterdorfer, Peter, Voelcker, Nicolas H.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2010
Fag:
Spectroscopy, Imaging, and Other Techniques
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931734/
https://ncbi.nlm.nih.gov/pubmed/20816080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.044
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