Detecting Protein Aggregates on Untreated Human Tissue Samples by Atomic Force Microscopy Recognition Imaging

We apply topography and recognition (TREC) imaging to the analysis of whole, untreated human tissue for what we believe to be the first time. Pseudoexfoliation syndrome (PEX), a well-known cause of irreversible blindness worldwide, is characterized by abnormal protein aggregation on the anterior len...

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Bibliographische Detailangaben
Hauptverfasser: Creasey, Rhiannon, Sharma, Shiwani, Craig, Jamie E., Gibson, Christopher T., Ebner, Andreas, Hinterdorfer, Peter, Voelcker, Nicolas H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2010
Schlagworte:
Spectroscopy, Imaging, and Other Techniques
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931734/
https://ncbi.nlm.nih.gov/pubmed/20816080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.044
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