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Simultaneous Topography and Recognition Imaging Using Force Microscopy

We present a method for simultaneously recording topography images and localizing specific binding sites with nm positional accuracy by combining dynamic force microscopy with single molecule recognition force spectroscopy. For this we used lysozyme adsorbed to mica, the functionality of which was c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Stroh, Cordula M., Ebner, Andreas, Geretschläger, Manfred, Freudenthaler, Günter, Kienberger, Ferry, Kamruzzahan, A. S. M., Smith-Gill, Sandra J., Gruber, Hermann J., Hinterdorfer, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304601/
https://ncbi.nlm.nih.gov/pubmed/15345574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.043331
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