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Complex Unfolding Kinetics of Single-Domain Proteins in the Presence of Force

Single-molecule force spectroscopy is providing unique, and sometimes unexpected, insights into the free-energy landscapes of proteins. Despite the complexity of the free-energy landscapes revealed by mechanical probes, forced unfolding experiments are often analyzed using one-dimensional models tha...

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Autors principals: Schlierf, Michael, Yew, Zu Thur, Rief, Matthias, Paci, Emanuele
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931718/
https://ncbi.nlm.nih.gov/pubmed/20816075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.039
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