Gene Knock-Outs of Inositol 1,4,5-Trisphosphate Receptors Types 1 and 2 Result in Perturbation of Cardiogenesis

BACKGROUND: Inositol 1,4,5-trisphosphate receptors (IP(3)R1, 2, and 3) are intracellular Ca(2+) release channels that regulate various vital processes. Although the ryanodine receptor type 2, another type of intracellular Ca(2+) release channel, has been shown to play a role in embryonic cardiomyocy...

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Detalhes bibliográficos
Main Authors: Uchida, Keiko, Aramaki, Megumi, Nakazawa, Maki, Yamagishi, Chihiro, Makino, Shinji, Fukuda, Keiichi, Nakamura, Takeshi, Takahashi, Takao, Mikoshiba, Katsuhiko, Yamagishi, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931702/
https://ncbi.nlm.nih.gov/pubmed/20824138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012500
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