A role for L-α-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells

BACKGROUND AND PURPOSE: Increased circulating levels of L-α-lysophosphatidylinositol (LPI) are associated with cancer and LPI is a potent, ligand for the G-protein-coupled receptor GPR55. Here we have assessed the modulation of breast cancer cell migration, orientation and polarization by LPI and GP...

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Main Authors: Ford, Lesley A, Roelofs, Anke J, Anavi-Goffer, Sharon, Mowat, Luisa, Simpson, Daniel G, Irving, Andrew J, Rogers, Michael J, Rajnicek, Ann M, Ross, Ruth A
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2010
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931574/
https://ncbi.nlm.nih.gov/pubmed/20590578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00743.x
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