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Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses

G protein-coupled receptor (GPR) 55 is sensitive to certain cannabinoids, it is expressed in the brain and, in cell cultures, it triggers mobilization of intracellular Ca(2+). However, the adaptive neurobiological significance of GPR55 remains unknown. Here, we use acute hippocampal slices and combi...

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Hlavní autoři: Sylantyev, Sergiy, Jensen, Thomas P., Ross, Ruth A., Rusakov, Dmitri A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612675/
https://ncbi.nlm.nih.gov/pubmed/23472002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211204110
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